Interference of intrinsic curvature of DNA by DNA-intercalating agents.
نویسندگان
چکیده
It has been demonstrated in our studies that the intrinsic curvature of DNA can be easily interrupted by low concentrations of chloroquine and ethidium bromide. In addition, the changes of DNA curvature caused by varying the concentration of these two DNA intercalators can be readily verified through using an atomic force microscope.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 11 شماره
صفحات -
تاریخ انتشار 2012